A CONSERVED FEMALE-SPECIFIC REQUIREMENT FOR THE GGT GENE IN MOSQUITO LARVAE FACILITATES RNAI-MEDIATED SEX SEPARATION IN MULTIPLE SPECIES OF DISEASE VECTOR MOSQUITOES

A Conserved Female-Specific Requirement for the GGT Gene in Mosquito Larvae Facilitates RNAi-Mediated Sex Separation in Multiple Species of Disease Vector Mosquitoes

Although several emerging mosquito control technologies are dependent on mass releases of adult males, methods of sex-sorting that can be implemented globally have not yet been established.RNAi screens led to the discovery of siRNA, which targets gamma-glutamyl transpeptidase (GGT), a gene which is well conserved in multiple species of mosquitoes a

read more

Prickle isoforms determine handedness of helical morphogenesis

Subcellular asymmetry directed by the Colloidal Silver planar cell polarity (PCP) signaling pathway orients numerous morphogenetic events in both invertebrates and vertebrates.Here, we describe a morphogenetic movement in which the intertwined socket and shaft cells of the Drosophila anterior wing margin mechanosensory bristles undergo PCP-directed

read more


Simultaneous Vitreoretinal Surgery and Penetrating Keratoplasty without a Keratoprosthesis or Endoscopy for Vitreoretinal Disease Associated with Corneal Opacity

We evaluated the visual outcome of combined penetrating keratoplasty (PKP) and 25G pars plana vitrectomy (PPV) performed without a temporary keratoprosthesis or endoscopy in a patient with vitreoretinal disease complicated by severe corneal opacity.The patient was a 68-year-old woman who had severe corneal opacity and silicone oil in her left eye a

read more